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KMID : 0605820110180010085
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Korean Journal of Pediatric Infectious Diseases
2011 Volume.18 No. 1 p.85 ~ p.90
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Three Cases of Prevention Therapy to Reduce Perinatal HIV Transmission
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Lee Jae-Yo
Park Hyang-Mi
Hwang Se-Hee
Kim Kyeung-Eun
Shin Hye-Jung
Kim Jae-Yoon
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Abstract
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In 2008, the Joint United Nations Programme on HIV/AIDS (UNAIDS) estimated that about 430,000 children worldwide became infected with HIV, mostly through mother-to-child transmission (MTCT) during pregnancy, labor, delivery, or breastfeeding. The MTCT prevention program proved to be feasible and effective in reduction of perinatal HIV transmission. Three babies born from HIV-infected mothers were admitted to the National Medical Center in 2009. Only two women received antiretroviral (ARV) therapy during pregnancy, labor, and after delivery, and their infants received zidovudine (AZT) for 6 weeks. The outcome, after a follow-up period of 4 months to 16 months, was favorable in all patients. Thus, we emphasize the need for expansion of antenatal HIV screening of pregnant women, implemented for early HIV diagnosis and effective ARV therapy for reduction of perinatal HIV transmission.
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KEYWORD
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HIV, Antiretroviral therapy
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